Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

Two new synthesized and characterized quinazoline Schiff bases 1 and 2 were investigated for anticancer activity against MCF-7 human breast cancer cell line. Compounds 1 and 2 demonstrated a remarkable antiproliferative effect, with an IC(50) value of 6.246 × 10(−6) mol/L and 5.910 × 10(−6) mol/L, r...

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Detalhes bibliográficos
Publicado no:ScientificWorldJournal
Main Authors: Faraj, Fadhil Lafta, Zahedifard, Maryam, Paydar, Mohammadjavad, Looi, Chung Yeng, Abdul Majid, Nazia, Ali, Hapipah Mohd, Ahmad, Noraini, Gwaram, Nura Suleiman, Abdulla, Mahmood Ameen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274848/
https://ncbi.nlm.nih.gov/pubmed/25548779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/212096
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