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CI-988 inhibits EGFR transactivation and proliferation caused by addition of CCK/Gastrin to lung cancer cells

Cholecystokinin (CCK) receptors are G-protein coupled receptors (GPCR) which are present on lung cancer cells. CCK-8 stimulates the proliferation of lung cancer cells, whereas the CCK2R receptor antagonist CI-988 inhibits proliferation. GPCR for some gastrointestinal hormones/neurotransmitters media...

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Detalles Bibliográficos
Publicado en:J Mol Neurosci
Autores principales: Moody, Terry W., Nuche-Berenguer, Bernardo, Moreno, Paola, Jensen, Robert T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479967/
https://ncbi.nlm.nih.gov/pubmed/25761747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-015-0533-6
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