Simultaneous Inhibition of EGFR/VEGFR and Cyclooxygenase-2 Targets Stemness-Related Pathways in Colorectal Cancer Cells

Despite the demonstrated benefits of anti-EGFR/VEGF targeted therapies in metastatic colorectal cancer (mCRC), many patients initially respond, but then show evidence of disease progression. New therapeutic strategies are needed to make the action of available drugs more efficient. Our study aimed t...

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Udgivet i:PLoS One
Main Authors: Valverde, Araceli, Peñarando, Jon, Cañas, Amanda, López-Sánchez, Laura M., Conde, Francisco, Hernández, Vanessa, Peralbo, Esther, López-Pedrera, Chary, de la Haba-Rodríguez, Juan, Aranda, Enrique, Rodríguez-Ariza, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479446/
https://ncbi.nlm.nih.gov/pubmed/26107817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131363
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