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Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors

INTRODUCTION: Protein denitrosylation by thioredoxin reductase (TrxR) is key for maintaining S-nitrosothiol (SNO) homeostasis, although its role in tumor progression is unknown. Therefore, the present study aimed to assess the role of altered SNO homeostasis in breast cancer cells. METHODS: The impa...

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Main Authors: Cañas, Amanda, López-Sánchez, Laura M, Valverde-Estepa, Araceli, Hernández, Vanessa, Fuentes, Elena, Muñoz-Castañeda, Juan R, López-Pedrera, Chary, De La Haba-Rodríguez, Juan R, Aranda, Enrique, Rodríguez-Ariza, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053140/
https://ncbi.nlm.nih.gov/pubmed/23216744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3366
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