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Transferrin-Mediated Cellular Iron Delivery

Essential to iron homeostasis is the transport of iron by the bilobal protein human serum transferrin (hTF). Each lobe (N- and C-lobe) of hTF forms a deep cleft which binds a single Fe(3+). Iron-bearing hTF in the blood binds tightly to the specific transferrin receptor (TFR), a homodimeric transmem...

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Publicat a:Curr Top Membr
Autors principals: Luck, Ashley N., Mason, Anne B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479283/
https://ncbi.nlm.nih.gov/pubmed/23046645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394390-3.00001-X
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