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Tuning the Attempt Frequency of Protein Folding Dynamics via Transition-State Rigidification: Application to Trp-Cage

[Image: see text] The attempt frequency or prefactor (k(0)) of the transition-state rate equation of protein folding kinetics has been estimated to be on the order of 10(6) s(–1), which is many orders of magnitude smaller than that of chemical reactions. Herein we use the mini-protein Trp-cage to sh...

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Vydáno v:J Phys Chem Lett
Hlavní autoři: Abaskharon, Rachel M., Culik, Robert M., Woolley, G. Andrew, Gai, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2015
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479204/
https://ncbi.nlm.nih.gov/pubmed/26120378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz502654q
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