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Tuning the Attempt Frequency of Protein Folding Dynamics via Transition-State Rigidification: Application to Trp-Cage
[Image: see text] The attempt frequency or prefactor (k(0)) of the transition-state rate equation of protein folding kinetics has been estimated to be on the order of 10(6) s(–1), which is many orders of magnitude smaller than that of chemical reactions. Herein we use the mini-protein Trp-cage to sh...
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| 發表在: | J Phys Chem Lett |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical Society
2015
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479204/ https://ncbi.nlm.nih.gov/pubmed/26120378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz502654q |
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