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Using D-Amino Acids to Delineate the Mechanism of Protein Folding: Application to Trp-cage
Using the miniprotein Trp-cage as a model, we show that D-amino acids can be used to facilitate the delineation of protein folding mechanism. Specifically, we study the folding-unfolding kinetics of three Trp-cage mutants where the native glycine residue near the C-terminus of the α-helix is replace...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844134/ https://ncbi.nlm.nih.gov/pubmed/24307748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphys.2013.01.021 |
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