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Clonidine and Dexmedetomidine Produce Antinociceptive Synergy in Mouse Spinal Cord

BACKGROUND: Synergy between drugs manifests with increased potency and/or efficacy of the combination relative to either agonist given alone. Synergy is typically observed between drugs of different classes, as is the case with the alpha-adrenergic-opioid receptor synergy often observed in preclinic...

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Publicado en:Anesthesiology
Main Authors: Fairbanks, Carolyn A., Kitto, Kelley F, Nguyen, Oanh, Stone, Laura S., Wilcox, George L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479173/
https://ncbi.nlm.nih.gov/pubmed/19212267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318195b51d
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