Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas

BACKGROUND: We previously demonstrated that patients with metastatic KRAS mutant lung cancers have a shorter survival compared to patients with KRAS wild type cancers. Recent reports have suggested different clinical outcomes and distinct activated signaling pathways depending on KRAS mutation subty...

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Udgivet i:J Thorac Oncol
Main Authors: Yu, Helena A., Sima, Camelia S., Shen, Ronglai, Kass, Samantha, Gainor, Justin, Shaw, Alice, Hames, Megan, Iams, Wade, Aston, Jonathan, Lovly, Christine M., Horn, Leora, Lydon, Christine, Oxnard, Geoffrey R., Kris, Mark G., Ladanyi, Marc, Riely, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479120/
https://ncbi.nlm.nih.gov/pubmed/25415430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000432
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