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Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis

BACKGROUND: Saturated fatty acids are toxic to liver cells and are believed to play a central role in the pathogenesis of non-alcoholic steatohepatitis. In experimental steatohepatitis induced by feeding mice a methionine-choline-deficient (MCD) diet, the degree of liver damage is related to dietary...

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Udgivet i:BMC Gastroenterol
Main Authors: Pierce, Andrew A., Pickens, Michael K., Siao, Kevin, Grenert, James P., Maher, Jacquelyn J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479079/
https://ncbi.nlm.nih.gov/pubmed/26103964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0298-y
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