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Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet

BACKGROUND: Methionine-choline-deficient (MCD) diets cause steatohepatitis in rodents and are used to model fatty liver disease in human beings. Recent studies have identified sucrose as a major contributor to MCD-related liver disease through its ability to promote hepatic de novo lipogenesis. AIMS...

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Detalhes bibliográficos
Main Authors: Pickens, Michael K., Ogata, Hisanobu, Soon, Russell K., Grenert, James P., Maher, Jacquelyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592570/
https://ncbi.nlm.nih.gov/pubmed/20536716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2010.02285.x
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