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Modeling diseases of noncoding unstable repeat expansions using mutant pluripotent stem cells
Pathogenic mutations involving DNA repeat expansions are responsible for over 20 different neuronal and neuromuscular diseases. All result from expanded tracts of repetitive DNA sequences (mostly microsatellites) that become unstable beyond a critical length when transmitted across generations. Near...
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| 出版年: | World J Stem Cells |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Baishideng Publishing Group Inc
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478629/ https://ncbi.nlm.nih.gov/pubmed/26131313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4252/wjsc.v7.i5.823 |
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