Cross-Reactivity, Epitope Spreading, and De Novo Immune Stimulation Are Possible Mechanisms of Cross-Protection of Nonvaccine Human Papillomavirus (HPV) Types in Recipients of HPV Therapeutic Vaccines

Numerous versions of human papillomavirus (HPV) therapeutic vaccines designed to treat individuals with established HPV infection, including those with cervical intraepithelial neoplasia (CIN), are in development because approved prophylactic vaccines are not effective once HPV infection is establis...

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Publicado en:Clin Vaccine Immunol
Autores principales: Nakagawa, Mayumi, Greenfield, William, Moerman-Herzog, Andrea, Coleman, Hannah N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478515/
https://ncbi.nlm.nih.gov/pubmed/25947147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00149-15
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