Cross-Reactivity, Epitope Spreading, and De Novo Immune Stimulation Are Possible Mechanisms of Cross-Protection of Nonvaccine Human Papillomavirus (HPV) Types in Recipients of HPV Therapeutic Vaccines

Numerous versions of human papillomavirus (HPV) therapeutic vaccines designed to treat individuals with established HPV infection, including those with cervical intraepithelial neoplasia (CIN), are in development because approved prophylactic vaccines are not effective once HPV infection is establis...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Nakagawa, Mayumi, Greenfield, William, Moerman-Herzog, Andrea, Coleman, Hannah N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478515/
https://ncbi.nlm.nih.gov/pubmed/25947147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00149-15
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