Distinct Gene Expression Profiles of Proximal and Distal Colorectal Cancer: Implications for Cytotoxic and Targeted Therapy

Colorectal cancer (CRC) is a heterogeneous disease with genetic profiles and clinical outcomes dependent on the anatomic location of the primary tumor. How location impacts the molecular makeup of a tumor and how prognostic and predictive biomarkers differ between proximal versus distal colon cancer...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Maus, Martin K.H., Hanna, Diana L., Stephens, Craig L., Astrow, Stephanie H., Yang, Dongyun, Grimminger, Peter P., Loupakis, Fotios, Hsiang, Jack H., Zeger, Gary, Wakatsuki, Takeru, Barzi, Afsaneh, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478287/
https://ncbi.nlm.nih.gov/pubmed/25532759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.73
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