Nuclear Factor Erythroid 2-like 2 Regulates Expression of Inositol 1,4,5-trisphosphate Receptor, Type 3 and Calcium Signaling in Cholangiocytes

BACKGROUND & AIMS: Most cholestatic disorders are caused by defects in cholangiocytes. The type 3 isoform of the inositol 1,4,5-trisphosphate receptor (ITPR3) is the intracellular calcium release channel detected most frequently in cholangiocytes. ITPR3 is required for bicarbonate secretion by b...

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Publicat a:Gastroenterology
Autors principals: Weerachayaphorn, Jittima, Amaya, Maria Jimena, Spirli, Carlo, Chansela, Piyachat, Mitchell, Kisha A., Ananthanarayanan, Meenakshisundaram, Nathanson, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478166/
https://ncbi.nlm.nih.gov/pubmed/25796361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.03.014
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