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Nuclear Factor Erythroid 2-like 2 Regulates Expression of Inositol 1,4,5-trisphosphate Receptor, Type 3 and Calcium Signaling in Cholangiocytes
BACKGROUND & AIMS: Most cholestatic disorders are caused by defects in cholangiocytes. The type 3 isoform of the inositol 1,4,5-trisphosphate receptor (ITPR3) is the intracellular calcium release channel detected most frequently in cholangiocytes. ITPR3 is required for bicarbonate secretion by b...
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Publicado no: | Gastroenterology |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478166/ https://ncbi.nlm.nih.gov/pubmed/25796361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.03.014 |
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