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How tough is Brittle Bone? Investigating Osteogenesis Imperfecta in Mouse Bone()

The multiscale hierarchical structure of bone is naturally optimized to resist fractures. In osteogenesis imperfecta, or brittle bone disease, genetic mutations affect the quality and/or quantity of collagen, dramatically increasing bone fracture risk. Here we reveal how the collagen defect results...

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Bibliografske podrobnosti
izdano v:J Bone Miner Res
Main Authors: Carriero, A., Zimmermann, E. A., Paluszny, A., Tang, S. Y., Bale, H., Busse, B., Alliston, T., Kazakia, G., Ritchie, R. O., Shefelbine, S. J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477967/
https://ncbi.nlm.nih.gov/pubmed/24420672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2172
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