How tough is Brittle Bone? Investigating Osteogenesis Imperfecta in Mouse Bone()

The multiscale hierarchical structure of bone is naturally optimized to resist fractures. In osteogenesis imperfecta, or brittle bone disease, genetic mutations affect the quality and/or quantity of collagen, dramatically increasing bone fracture risk. Here we reveal how the collagen defect results...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Carriero, A., Zimmermann, E. A., Paluszny, A., Tang, S. Y., Bale, H., Busse, B., Alliston, T., Kazakia, G., Ritchie, R. O., Shefelbine, S. J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477967/
https://ncbi.nlm.nih.gov/pubmed/24420672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2172
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