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Increasing inflationary T-cell responses following transient depletion of MCMV-specific memory T cells

Murine CMV (MCMV) infection induces effector CD8(+) T cells that continue to increase in frequency after acute infection (“inflation”) and are stably maintained at a high frequency, with up to 20% of the CD8(+) T-cell compartment being specific for one epitope, although the flexibility and turnover...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Sims, Stuart, Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477908/
https://ncbi.nlm.nih.gov/pubmed/25331015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445016
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