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CD73 Is Dispensable for the Regulation of Inflationary CD8(+) T-Cells after Murine Cytomegalovirus Infection and Adenovirus Immunisation

The ecto-5'-nucleotidase (CD73) is expressed by T-cell subsets, myeloid derived suppressive cells and endothelial cells. It works in conjunction with CD39 to regulate the formation and degradation of adenosine in vivo. Adenosine has previously been shown to suppress the proliferation and cytoki...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Sims, Stuart, Colston, Julia, Emery, Vince, Klenerman, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260835/
https://ncbi.nlm.nih.gov/pubmed/25490556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114323
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