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The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma

Ewing Sarcoma is a biologically aggressive bone and soft tissue malignancy affecting children and young adults. Ewing Sarcoma pathogenesis is driven by EWS/Ets fusion oncoproteins, of which EWS/Fli1 is the most common. We have previously shown that microRNAs (miRs) regulated by EWS/Fli1 contribute t...

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Bibliographic Details
Published in:Oncogene
Main Authors: Parrish, JK, Sechler, M, Winn, RA, Jedlicka, P
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477825/
https://ncbi.nlm.nih.gov/pubmed/24362521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.541
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