Central Role of ULK1 in Type I Interferon Signaling

We provide evidence that the Unc-51-like kinase 1 (ULK1) is activated during engagement of the Type I IFN receptor (IFNR). Our studies demonstrate that the function of ULK1 is required for gene transcription mediated via IFN-stimulated response elements (ISRE) and IFNγ activation site (GAS) elements...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Saleiro, Diana, Mehrotra, Swarna, Kroczynska, Barbara, Beauchamp, Elspeth M., Lisowski, Pawel, Majchrzak-Kita, Beata, Bhagat, Tushar D., Stein, Brady L., McMahon, Brandon, Altman, Jessica K., Kosciuczuk, Ewa M., Baker, Darren P., Jie, Chunfa, Jafari, Nadereh, Thompson, Craig B., Levine, Ross L., Fish, Eleanor N., Verma, Amit K., Platanias, Leonidas C.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477687/
https://ncbi.nlm.nih.gov/pubmed/25892232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.056
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