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Mycobacterial glycolipids di-O-acylated trehalose and tri-O-acylated trehalose downregulate inducible nitric oxide synthase and nitric oxide production in macrophages

BACKGROUND: Tuberculosis (TB) remains a serious human health problem that affects millions of people in the world. Understanding the biology of Mycobacterium tuberculosis (Mtb) is essential for tackling this devastating disease. Mtb possesses a very complex cell envelope containing a variety of lipi...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Espinosa-Cueto, Patricia, Escalera-Zamudio, Marina, Magallanes-Puebla, Alejandro, López-Marín, Luz María, Segura-Salinas, Erika, Mancilla, Raúl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477496/
https://ncbi.nlm.nih.gov/pubmed/26100760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0102-3
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