Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility

BACKGROUND: Guanine nucleotide exchange factors (GEFs) activate small GTPases that are involved in several cellular functions. cAMP-guanine nucleotide exchange factor II (cAMP-GEF II) acts as a target for cAMP independently of protein kinase A (PKA) and functions as a GEF for Rap1 and Rap2. Although...

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Publicado no:Mol Brain
Main Authors: Lee, Kyungmin, Kobayashi, Yuki, Seo, Hyunhyo, Kwak, Ji-Hye, Masuda, Akira, Lim, Chae-Seok, Lee, Hye-Ryeon, Kang, SukJae Joshua, Park, Pojeong, Sim, Su-Eon, Kogo, Naomi, Kawasaki, Hiroaki, Kaang, Bong-Kiun, Itohara, Shigeyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477293/
https://ncbi.nlm.nih.gov/pubmed/26104314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0130-1
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