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Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depression

Phosphoinositide 3-kinases (PI3Ks) play key roles in synaptic plasticity and cognitive functions in the brain. We recently found that genetic deletion of PI3Kγ, the only known member of class IB PI3Ks, results in impaired N-methyl-(D)-aspartate receptor-dependent long-term depression (NMDAR-LTD) in...

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Detalhes bibliográficos
Main Authors: Sim, Su-Eon, Lee, Hye-Ryeon, Kim, Jae-Ick, Choi, Sun-Lim, Bakes, Joseph, Jang, Deok-Jin, Lee, Kyungmin, Han, Kihoon, Kim, Eunjoon, Kaang, Bong-Kiun
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133848/
https://ncbi.nlm.nih.gov/pubmed/23433113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.2.143
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