Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depression

Phosphoinositide 3-kinases (PI3Ks) play key roles in synaptic plasticity and cognitive functions in the brain. We recently found that genetic deletion of PI3Kγ, the only known member of class IB PI3Ks, results in impaired N-methyl-(D)-aspartate receptor-dependent long-term depression (NMDAR-LTD) in...

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Hlavní autoři: Sim, Su-Eon, Lee, Hye-Ryeon, Kim, Jae-Ick, Choi, Sun-Lim, Bakes, Joseph, Jang, Deok-Jin, Lee, Kyungmin, Han, Kihoon, Kim, Eunjoon, Kaang, Bong-Kiun
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2013
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133848/
https://ncbi.nlm.nih.gov/pubmed/23433113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.2.143
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