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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.

The phosphatidylinositol 3-kinase (PI 3-K) becomes activated when quiescent cells are stimulated with a variety of growth factors. We have microinjected antibodies specific for the p110 alpha subunit of the PI 3-K into quiescent fibroblasts and tested their effect on the ability of growth factors to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Roche, S, Koegl, M, Courtneidge, S A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8090789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.9185
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