The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.
The phosphatidylinositol 3-kinase (PI 3-K) becomes activated when quiescent cells are stimulated with a variety of growth factors. We have microinjected antibodies specific for the p110 alpha subunit of the PI 3-K into quiescent fibroblasts and tested their effect on the ability of growth factors to...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1994
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8090789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.9185 |
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