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The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines

Inflammasomes are caspase-1 activating, molecular inflammatory machines that proteolytically mature pro-inflammatory cytokines and induce pyroptotic cell death during innate immune responses. Recent structural studies of proteins that constitute inflammasomes have yielded fresh insights into their a...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Hauenstein, Arthur V., Zhang, Liman, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476925/
https://ncbi.nlm.nih.gov/pubmed/25881155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.03.014
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