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The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines
Inflammasomes are caspase-1 activating, molecular inflammatory machines that proteolytically mature pro-inflammatory cytokines and induce pyroptotic cell death during innate immune responses. Recent structural studies of proteins that constitute inflammasomes have yielded fresh insights into their a...
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| Udgivet i: | Curr Opin Struct Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476925/ https://ncbi.nlm.nih.gov/pubmed/25881155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.03.014 |
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