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Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling

AIM: To examine the potential anti-tumor activity of paeoniflorin in the human gastric carcinoma cell line MGC-803. METHODS: Cell viability and cytotoxic effects in MGC-803 cells were analyzed using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and lactate dehydrogenase assay, respe...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Zheng, Yong-Bin, Xiao, Gao-Chun, Tong, Shi-Lun, Ding, Yu, Wang, Qiu-Shuang, Li, Sheng-Bo, Hao, Zhi-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476881/
https://ncbi.nlm.nih.gov/pubmed/26109806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i23.7197
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