Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia

BACKGROUND: Recombinant factor VIIa (rFVIIa) is registered for use in haemophilia with inhibitors and other rare bleeding disorders, but has also been used in various other clinical conditions to terminate life-threatening bleeding. Underlying conditions (e.g. coagulopathy) and dosing may affect tre...

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Vydáno v:PLoS One
Hlavní autoři: Spronk, Henri M. H., Braunschweig, Till, Rossaint, Rolf, Wüst, Dirk C., van Oerle, Rene, Lauritzen, Brian, Tolba, Rene, Grottke, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476676/
https://ncbi.nlm.nih.gov/pubmed/26098426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113979
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