The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression

The phosphatase and actin regulator 1 (PHACTR1) locus is a very commonly identified hit in genome-wide association studies investigating coronary artery disease and myocardial infarction (MI). However, the function of PHACTR1 in the heart is still unknown. We characterized the mechanisms regulating...

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Publicado en:PLoS One
Main Authors: Kelloniemi, Annina, Szabo, Zoltan, Serpi, Raisa, Näpänkangas, Juha, Ohukainen, Pauli, Tenhunen, Olli, Kaikkonen, Leena, Koivisto, Elina, Bagyura, Zsolt, Kerkelä, Risto, Leosdottir, Margret, Hedner, Thomas, Melander, Olle, Ruskoaho, Heikki, Rysä, Jaana
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476650/
https://ncbi.nlm.nih.gov/pubmed/26098115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130502
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