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Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte Differentiation

Intraflagellar transport proteins (IFT) play important roles in cilia formation and organ development. Partial loss of IFT80 function leads Jeune asphyxiating thoracic dystrophy (JATD) or short-rib polydactyly (SRP) syndrome type III, displaying narrow thoracic cavity and multiple cartilage anomalie...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Yuan, Xue, Yang, Shuying
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476593/
https://ncbi.nlm.nih.gov/pubmed/26098911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130618
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