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Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in TNF Responders

OBJECTIVE: To establish whether the analysis of whole blood gene expression can be useful in predicting or monitoring response to anti-TNF therapy in RA. METHODS: Whole blood RNA (PAXgene) was obtained at baseline and 14 weeks on three independent cohorts with a combined total of 250 patients with r...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Oswald, Michaela, Curran, Mark, Lamberth, Sarah, Townsend, Robert, Hamilton, Jennifer D., Chernoff, David N., Carulli, John, Townsend, Michael, Weinblatt, Michael, Kern, Marlena, Pond, Cassandra, Lee, Annette, Gregersen, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476407/
https://ncbi.nlm.nih.gov/pubmed/25371395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38947
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