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CARTILAGE CONSTRUCTS ENGINEERED FROM CHONDROCYTES OVEREXPRESSING IGF-I IMPROVE THE REPAIR OF OSTEOCHONDRAL DEFECTS IN A RABBIT MODEL

Tissue engineering combined with gene therapy is a promising approach for promoting articular cartilage repair. Here, we tested the hypothesis that engineered cartilage with chondrocytes over expressing a human insulin-like growth factor I (IGF-I) gene can enhance the repair of osteochondral defects...

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Detalhes bibliográficos
Publicado no:Eur Cell Mater
Main Authors: Madry, Henning, Kaul, Gunter, Zurakowski, David, Vunjak-Novakovic, Gordana, Cucchiarini, Magali
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476264/
https://ncbi.nlm.nih.gov/pubmed/23588785
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