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Inhibition of Cancer Cell Proliferation and Breast Tumor Targeting of pHLIP-Monomethyl Auristatin E Conjugates

Localized delivery is vital for the successful development of novel and effective therapeutics for the treatment of cancer. The targeting and delivery described herein is based on the pH(Low) Insertion Peptide (pHLIP), a unique delivery peptide that can selectively target tumors in mice and transloc...

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Vydáno v:Mol Pharm
Hlavní autoři: Burns, Kelly E., Robinson, Matthew K., Théveninr, Damien
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476257/
https://ncbi.nlm.nih.gov/pubmed/25741818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500779k
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