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Inhibition of Cancer Cell Proliferation and Breast Tumor Targeting of pHLIP-Monomethyl Auristatin E Conjugates

Localized delivery is vital for the successful development of novel and effective therapeutics for the treatment of cancer. The targeting and delivery described herein is based on the pH(Low) Insertion Peptide (pHLIP), a unique delivery peptide that can selectively target tumors in mice and transloc...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Burns, Kelly E., Robinson, Matthew K., Théveninr, Damien
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476257/
https://ncbi.nlm.nih.gov/pubmed/25741818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500779k
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