High-Density IgE Recognition of the Major Grass Pollen Allergen Phl p 1 Revealed with Single-Chain IgE Antibody Fragments Obtained by Combinatorial Cloning

The timothy grass pollen allergen Phl p 1 belongs to the group 1 of highly cross-reactive grass pollen allergens with a molecular mass of ~25–30 kDa. Group 1 allergens are recognized by >95% of grass pollen allergic patients. We investigated the IgE recognition of Phl p 1 using allergen-specific...

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Bibliographic Details
Published in:J Immunol
Main Authors: Madritsch, Christoph, Gadermaier, Elisabeth, Roder, Uwe W., Lupinek, Christian, Valenta, Rudolf, Flicker, Sabine
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476238/
https://ncbi.nlm.nih.gov/pubmed/25637023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402185
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