Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

BACKGROUND: Aberrant DNA methylation at the 5-carbon on cytosine residues (5mC) in CpG dinucleotides is probably the most extensively characterized epigenetic modification in colon cancer. It has been suggested that the loss of adenomatous polyposis coli (APC) function initiates tumorigenesis and th...

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發表在:Cell Biosci
Main Authors: Guo, Yue, Lee, Jong Hun, Shu, Limin, Huang, Ying, Li, Wenji, Zhang, Chengyue, Yang, Anne Yuqing, Boyanapalli, Sarandeep SS, Perekatt, Ansu, Hart, Ronald P, Verzi, Michael, Kong, Ah-Ng Tony
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476183/
https://ncbi.nlm.nih.gov/pubmed/26101583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0013-2
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