Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

BACKGROUND: Aberrant DNA methylation at the 5-carbon on cytosine residues (5mC) in CpG dinucleotides is probably the most extensively characterized epigenetic modification in colon cancer. It has been suggested that the loss of adenomatous polyposis coli (APC) function initiates tumorigenesis and th...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Guo, Yue, Lee, Jong Hun, Shu, Limin, Huang, Ying, Li, Wenji, Zhang, Chengyue, Yang, Anne Yuqing, Boyanapalli, Sarandeep SS, Perekatt, Ansu, Hart, Ronald P, Verzi, Michael, Kong, Ah-Ng Tony
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476183/
https://ncbi.nlm.nih.gov/pubmed/26101583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0013-2
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