Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

BACKGROUND: Aberrant DNA methylation at the 5-carbon on cytosine residues (5mC) in CpG dinucleotides is probably the most extensively characterized epigenetic modification in colon cancer. It has been suggested that the loss of adenomatous polyposis coli (APC) function initiates tumorigenesis and th...

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Dades bibliogràfiques
Publicat a:Cell Biosci
Autors principals: Guo, Yue, Lee, Jong Hun, Shu, Limin, Huang, Ying, Li, Wenji, Zhang, Chengyue, Yang, Anne Yuqing, Boyanapalli, Sarandeep SS, Perekatt, Ansu, Hart, Ronald P, Verzi, Michael, Kong, Ah-Ng Tony
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476183/
https://ncbi.nlm.nih.gov/pubmed/26101583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0013-2
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