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Selection and Evolution of Enzymes from a Partially Randomized Non-Catalytic Scaffold

Enzymes are exceptional catalysts that facilitate a wide variety of reactions under mild conditions, achieving high rate enhancements with excellent chemo-, regio- and stereoselectivities. There is considerable interest in developing new enzymes for the synthesis of chemicals and pharmaceuticals(1–3...

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Publicado en:Nature
Autores principales: Seelig, Burckhard, Szostak, Jack W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476047/
https://ncbi.nlm.nih.gov/pubmed/17700701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06032
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