Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum

The identification of new pathways governing myelination provides innovative avenues for remyelination. Liver X receptors (LXRs) α and β are nuclear receptors activated by oxysterols that originated from the oxidation of cholesterol. They are crucial for cholesterol homeostasis, a major lipid consti...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Meffre, Delphine, Shackleford, Ghjuvan’Ghjacumu, Hichor, Mehdi, Gorgievski, Victor, Tzavara, Eleni T., Trousson, Amalia, Ghoumari, Abdel M., Deboux, Cyrille, Nait Oumesmar, Brahim, Liere, Philippe, Schumacher, Michael, Baulieu, Etienne-Emile, Charbonnier, Frédéric, Grenier, Julien, Massaad, Charbel
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475952/
https://ncbi.nlm.nih.gov/pubmed/26023184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424951112
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