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Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation

In mammals the stress-inducible expression of genes encoding heat shock proteins is under the control of the heat shock transcription factor 1 (HSF1). Activation of HSF1 is a multistep process, involving trimerization, acquisition of DNA-binding and transcriptional activities, which coincide with se...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Budzyński, Marek A., Puustinen, Mikael C., Joutsen, Jenny, Sistonen, Lea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475925/
https://ncbi.nlm.nih.gov/pubmed/25963659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00816-14
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