Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining

The nonhomologous end-joining (NHEJ) pathway is essential for the preservation of genome integrity, as it efficiently repairs DNA double-strand breaks (DSBs). Previous biochemical and genetic investigations have indicated that, despite the importance of this pathway, the entire complement of genes r...

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Publicado en:Mol Cell Biol
Autores principales: Jessulat, Matthew, Malty, Ramy H., Nguyen-Tran, Diem-Hang, Deineko, Viktor, Aoki, Hiroyuki, Vlasblom, James, Omidi, Katayoun, Jin, Ke, Minic, Zoran, Hooshyar, Mohsen, Burnside, Daniel, Samanfar, Bahram, Phanse, Sadhna, Freywald, Tanya, Prasad, Bhanu, Zhang, Zhaolei, Vizeacoumar, Franco, Krogan, Nevan J., Freywald, Andrew, Golshani, Ashkan, Babu, Mohan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475915/
https://ncbi.nlm.nih.gov/pubmed/25963654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00007-15
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