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Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining
The nonhomologous end-joining (NHEJ) pathway is essential for the preservation of genome integrity, as it efficiently repairs DNA double-strand breaks (DSBs). Previous biochemical and genetic investigations have indicated that, despite the importance of this pathway, the entire complement of genes r...
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Izdano u: | Mol Cell Biol |
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Glavni autori: | , , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Microbiology
2015
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475915/ https://ncbi.nlm.nih.gov/pubmed/25963654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00007-15 |
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