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N(6)-methyl-adenosine (m6A) marks primary microRNAs for processing
The first step in the biogenesis of microRNAs is the processing of primary microRNAs (pri-miRNAs) by the microprocessor complex, composed of the RNA binding protein DGCR8 and the ribonuclease type III DROSHA(1–4). This initial event requires the recognition of the junction between the stem and the f...
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| Pubblicato in: | Nature |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475635/ https://ncbi.nlm.nih.gov/pubmed/25799998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14281 |
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