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Structural analysis of Der p 1-antibody complexes and comparison with complexes of proteins or peptides with monoclonal antibodies
Der p 1 is a major allergen from the house dust mite Dermatophagoides pteronyssinus that belongs to the papain-like cysteine protease family. To investigate the antigenic determinants of Der p 1, we determined two crystal structures of Der p 1 in complex with the Fab fragments of mAbs 5H8 or 10B9. E...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475478/ https://ncbi.nlm.nih.gov/pubmed/26026055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402199 |
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