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Carbohydrates contribute to the interactions between cockroach allergen Bla g 2 and a monoclonal antibody

The crystal structure of a murine monoclonal antibody, 4C3, that binds to the C-terminal lobe of the cockroach allergen Bla g 2, has been solved at 1.8 Å resolution. Binding of 4C3 involves different types of molecular interactions with its epitope compared to the monoclonal antibody 7C11, which bin...

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Detalhes bibliográficos
Main Authors: Li, Mi, Gustchina, Alla, Glesner, Jill, Wünschmann, Sabina, Vailes, Lisa D., Chapman, Martin D., Pomés, Anna, Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099132/
https://ncbi.nlm.nih.gov/pubmed/21123808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002318
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