The Presence of a Galactosamine Substituent on the Arabinogalactan of Mycobacterium tuberculosis Abrogates Full Maturation of Human Peripheral Blood Monocyte-Derived Dendritic cells and Increases Secretion of IL-10

Slow-growing and pathogenic Mycobacterium spp. are characterized by the presence of galactosamine (GalN) that modifies the interior branched arabinosyl residues of the arabinogalactan (AG) that is a major heteropolysaccharide cell wall component. The availability of null mutants of the polyprenyl-ph...

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Publicat a:Tuberculosis (Edinb)
Autors principals: Wheat, William H., Dhouib, Rabeb, Angala, Shiva K., Larrouy-Maumus, Gérald, Dobos, Karen, Nigou, Jérôme, Spencer, John S., Jackson, Mary
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475442/
https://ncbi.nlm.nih.gov/pubmed/26048627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2015.04.002
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