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Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions

In response to DNA damage, checkpoint signalling protects genome integrity at the cost of repressing cell cycle progression and DNA replication. Mechanisms for checkpoint down-regulation are therefore necessary for proper cellular proliferation. We recently uncovered a phosphatase-independent mechan...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Cussiol, José R, Jablonowski, Carolyn M, Yimit, Askar, Brown, Grant W, Smolka, Marcus B
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475403/
https://ncbi.nlm.nih.gov/pubmed/25896509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490834
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