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Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions
In response to DNA damage, checkpoint signalling protects genome integrity at the cost of repressing cell cycle progression and DNA replication. Mechanisms for checkpoint down-regulation are therefore necessary for proper cellular proliferation. We recently uncovered a phosphatase-independent mechan...
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| Pubblicato in: | EMBO J |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475403/ https://ncbi.nlm.nih.gov/pubmed/25896509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490834 |
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